In a shallow 2-quart microwave-safe dish with a lid, combine rice, wine, oil, garlic, red-pepper flakes, and 2 cups water; season with salt and pepper.
Cover, and microwave on high until rice is tender and liquid is absorbed, 20 minutes, stirring twice during cooking.
Stir in shrimp and lemon wedges; cover, and microwave 3 minutes more.
Let stand, covered, until shrimp are opaque throughout, 2 minutes.